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Drosophila models of prionopathies: insight into prion protein function, transmission, and neurotoxicity

Prion diseases (PrD) are unique neurodegenerative conditions that can present with sporadic, genetic, and infectious etiologies. The agent responsible for these pathologies in humans and mammals is a misfolded conformation of the prion protein (PrP), a membrane-anchored protein highly expressed in t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Curr Opin Genet Dev
Päätekijät: Fernandez-Funez, Pedro, Sanchez-Garcia, Jonatan, Rincon-Limas, Diego E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474952/
https://ncbi.nlm.nih.gov/pubmed/28415023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.03.013
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