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Drosophila models of prionopathies: insight into prion protein function, transmission, and neurotoxicity

Prion diseases (PrD) are unique neurodegenerative conditions that can present with sporadic, genetic, and infectious etiologies. The agent responsible for these pathologies in humans and mammals is a misfolded conformation of the prion protein (PrP), a membrane-anchored protein highly expressed in t...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Fernandez-Funez, Pedro, Sanchez-Garcia, Jonatan, Rincon-Limas, Diego E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474952/
https://ncbi.nlm.nih.gov/pubmed/28415023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.03.013
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