Viral and cellular mRNA-specific activators harness PABP and eIF4G to promote translation initiation downstream of cap binding

Regulation of mRNA translation is a major control point for gene expression and is critical for life. Of central importance is the complex between cap-bound eukaryotic initiation factor 4E (eIF4E), eIF4G, and poly(A) tail-binding protein (PABP) that circularizes mRNAs, promoting translation and stab...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Smith, Richard W. P., Anderson, Ross C., Larralde, Osmany, Smith, Joel W. S., Gorgoni, Barbara, Richardson, William A., Malik, Poonam, Graham, Sheila V., Gray, Nicola K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474791/
https://ncbi.nlm.nih.gov/pubmed/28559344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610417114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados