Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation

IRES-mediated translation of key cell fate regulating genes has been implicated in tumorigenesis. Concerted action of canonical eukaryotic initiation factors and IRES transacting factors (ITAFs) was shown to regulate cellular IRES mediated translation; however, the precise molecular mechanism of rib...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:RNA Biol
Hlavní autoři: Thakor, Nehal, Smith, M. Duane, Roberts, Luc, Faye, Mame Daro, Patel, Harshil, Wieden, Hans-Joachim, Cate, Jamie H. D., Holcik, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449081/
https://ncbi.nlm.nih.gov/pubmed/26828225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1137419
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky