Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation

IRES-mediated translation of key cell fate regulating genes has been implicated in tumorigenesis. Concerted action of canonical eukaryotic initiation factors and IRES transacting factors (ITAFs) was shown to regulate cellular IRES mediated translation; however, the precise molecular mechanism of rib...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Thakor, Nehal, Smith, M. Duane, Roberts, Luc, Faye, Mame Daro, Patel, Harshil, Wieden, Hans-Joachim, Cate, Jamie H. D., Holcik, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449081/
https://ncbi.nlm.nih.gov/pubmed/26828225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1137419
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