Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation

IRES-mediated translation of key cell fate regulating genes has been implicated in tumorigenesis. Concerted action of canonical eukaryotic initiation factors and IRES transacting factors (ITAFs) was shown to regulate cellular IRES mediated translation; however, the precise molecular mechanism of rib...

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Détails bibliographiques
Publié dans:RNA Biol
Auteurs principaux: Thakor, Nehal, Smith, M. Duane, Roberts, Luc, Faye, Mame Daro, Patel, Harshil, Wieden, Hans-Joachim, Cate, Jamie H. D., Holcik, Martin
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449081/
https://ncbi.nlm.nih.gov/pubmed/26828225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1137419
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