Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation

IRES-mediated translation of key cell fate regulating genes has been implicated in tumorigenesis. Concerted action of canonical eukaryotic initiation factors and IRES transacting factors (ITAFs) was shown to regulate cellular IRES mediated translation; however, the precise molecular mechanism of rib...

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Bibliografiske detaljer
Udgivet i:RNA Biol
Main Authors: Thakor, Nehal, Smith, M. Duane, Roberts, Luc, Faye, Mame Daro, Patel, Harshil, Wieden, Hans-Joachim, Cate, Jamie H. D., Holcik, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449081/
https://ncbi.nlm.nih.gov/pubmed/26828225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1137419
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