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A helicase-independent activity of eIF4A in promoting mRNA recruitment to the human ribosome

In the scanning model of translation initiation, the decoding site and latch of the 40S subunit must open to allow the recruitment and migration of messenger RNA (mRNA); however, the precise molecular details for how initiation factors regulate mRNA accommodation into the decoding site have not yet...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sokabe, Masaaki, Fraser, Christopher S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474785/
https://ncbi.nlm.nih.gov/pubmed/28559306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620426114
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