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A helicase-independent activity of eIF4A in promoting mRNA recruitment to the human ribosome

In the scanning model of translation initiation, the decoding site and latch of the 40S subunit must open to allow the recruitment and migration of messenger RNA (mRNA); however, the precise molecular details for how initiation factors regulate mRNA accommodation into the decoding site have not yet...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Sokabe, Masaaki, Fraser, Christopher S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474785/
https://ncbi.nlm.nih.gov/pubmed/28559306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620426114
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