Direct Stimulation of Translation by the Multifunctional Herpesvirus ICP27 Protein

Herpes simplex virus type 1 (HSV-1) ICP27 protein is an essential regulator of viral gene expression with roles at various levels of RNA metabolism in the nucleus. Using the tethered function assay, we showed a cytoplasmic activity for ICP27 in directly enhancing mRNA translation in vivo in the abse...

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Detalhes bibliográficos
Main Authors: Larralde, Osmany, Smith, Richard W. P., Wilkie, Gavin S., Malik, Poonam, Gray, Nicola K., Clements, J. Barklie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346932/
https://ncbi.nlm.nih.gov/pubmed/16415034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1588-1591.2006
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