The loss of CCR6+ and CD161+ CD4+ T cell homeostasis contributes to disease progression in SIV-infected rhesus macaques

While previous studies have shown that CD4+ T cells expressing CCR6 and CD161 are depleted from blood during HIV infection, the mechanisms underlying their loss remain unclear. In this study, we investigated how the homeostasis of CCR6+ and CD161+ CD4+ T cells contributes to SIV disease progression...

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發表在:Mucosal Immunol
Main Authors: McGary, Colleen S., Alvarez, Xavier, Harrington, Sean, Cervasi, Barbara, Ryan, Emily S., Iriele, Robin I., Paganini, Sara, Harper, Justin, Easley, Kirk, Silvestri, Guido, Ansari, Aftab A., Lichterfeld, Mathias, Micci, Luca, Paiardini, Mirko
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474141/
https://ncbi.nlm.nih.gov/pubmed/28051083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.116
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