The loss of CCR6+ and CD161+ CD4+ T cell homeostasis contributes to disease progression in SIV-infected rhesus macaques

While previous studies have shown that CD4+ T cells expressing CCR6 and CD161 are depleted from blood during HIV infection, the mechanisms underlying their loss remain unclear. In this study, we investigated how the homeostasis of CCR6+ and CD161+ CD4+ T cells contributes to SIV disease progression...

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Gepubliceerd in:Mucosal Immunol
Hoofdauteurs: McGary, Colleen S., Alvarez, Xavier, Harrington, Sean, Cervasi, Barbara, Ryan, Emily S., Iriele, Robin I., Paganini, Sara, Harper, Justin, Easley, Kirk, Silvestri, Guido, Ansari, Aftab A., Lichterfeld, Mathias, Micci, Luca, Paiardini, Mirko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474141/
https://ncbi.nlm.nih.gov/pubmed/28051083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.116
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