Maintenance of Intestinal Th17 Cells and Reduced Microbial Translocation in SIV-infected Rhesus Macaques Treated with Interleukin (IL)-21

In pathogenic HIV and SIV infections of humans and rhesus macaques (RMs), preferential depletion of CD4(+) Th17 cells correlates with mucosal immune dysfunction and disease progression. Interleukin (IL)-21 promotes differentiation of Th17 cells, long-term maintenance of functional CD8(+) T cells, an...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Pallikkuth, Suresh, Micci, Luca, Ende, Zachary S., Iriele, Robin I., Cervasi, Barbara, Lawson, Benton, McGary, Colleen S., Rogers, Kenneth A., Else, James G., Silvestri, Guido, Easley, Kirk, Estes, Jacob D., Villinger, Francois, Pahwa, Savita, Paiardini, Mirko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701718/
https://ncbi.nlm.nih.gov/pubmed/23853592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003471
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