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Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats
The peptide HsTX1[R14A] is a potent and selective blocker of the voltage-gated potassium channel Kv1.3, which is a highly promising target for the treatment of autoimmune diseases and other conditions. In order to assess the biodistribution of this peptide, it was conjugated with NOTA and radiolabel...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473807/ https://ncbi.nlm.nih.gov/pubmed/28623364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03998-x |
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