טוען...
Altered NADH/NAD(+) Ratio Mediates Coresistance to Isoniazid and Ethionamide in Mycobacteria
The front-line antituberculosis drug isoniazid (INH) and the related drug ethionamide (ETH) are prodrugs that upon activation inhibit the synthesis of mycolic acids, leading to bactericidal activity. Coresistance to INH and ETH can be mediated by dominant mutations in the target gene inhA, encoding...
שמור ב:
| הוצא לאור ב: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
2005
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC547332/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15673755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.2.708-720.2005 |
| תגים: |
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