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Conformational changes at cytoplasmic intersubunit interactions control Kir channel gating

The defining structural feature of inward-rectifier potassium (Kir) channels is the unique Kir cytoplasmic domain. Recently we showed that salt bridges located at the cytoplasmic domain subunit interfaces (CD-Is) of eukaryotic Kir channels control channel gating via stability of a novel inactivated...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Wang, Shizhen, Borschel, William F., Heyman, Sarah, Hsu, Phillip, Nichols, Colin G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2017
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473215/
https://ncbi.nlm.nih.gov/pubmed/28446610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.785154
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