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Conformational changes at cytoplasmic intersubunit interactions control Kir channel gating
The defining structural feature of inward-rectifier potassium (Kir) channels is the unique Kir cytoplasmic domain. Recently we showed that salt bridges located at the cytoplasmic domain subunit interfaces (CD-Is) of eukaryotic Kir channels control channel gating via stability of a novel inactivated...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473215/ https://ncbi.nlm.nih.gov/pubmed/28446610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.785154 |
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