Regulatory switch at the cytoplasmic interface controls TRPV channel gating

Temperature-sensitive transient receptor potential vanilloid (thermoTRPV) channels are activated by ligands and heat, and are involved in various physiological processes. ThermoTRPV channels possess a large cytoplasmic ring consisting of N-terminal ankyrin repeat domains (ARD) and C-terminal domains...

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Sparad:
Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Zubcevic, Lejla, Borschel, William F, Hsu, Allen L, Borgnia, Mario J, Lee, Seok-Yong
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2019
Ämnen:
Structural Biology and Molecular Biophysics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538378/
https://ncbi.nlm.nih.gov/pubmed/31070581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47746
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