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Intersubunit conformational changes mediate epithelial sodium channel gating
The epithelial Na(+) channel (ENaC) functions as a pathway for Na(+) absorption in the kidney and lung, where it is crucial for Na(+) homeostasis and blood pressure regulation. However, the basic mechanisms that control ENaC gating are poorly understood. Here we define a role in gating for residues...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178938/ https://ncbi.nlm.nih.gov/pubmed/25225551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411208 |
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