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Extracellular Chloride Regulates the Epithelial Sodium Channel

The extracellular domain of the epithelial sodium channel ENaC is exposed to a wide range of Cl(−) concentrations in the kidney and in other epithelia. We tested whether Cl(−) alters ENaC activity. In Xenopus oocytes expressing human ENaC, replacement of Cl(−) with SO(4)(2−), H(2)PO(4)(−), or SCN(−)...

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Bibliografische gegevens
Hoofdauteurs: Collier, Daniel M., Snyder, Peter M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785562/
https://ncbi.nlm.nih.gov/pubmed/19713212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046771
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