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Structural rearrangements underlying ligand-gating in Kir channels
Inward rectifier potassium (Kir) channels are physiologically regulated by a wide range of ligands that all act on a common gate, although structural details of gating are unclear. Here we show, using small molecule fluorescent probes attached to introduced cysteines, the molecular motions associate...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277880/ https://ncbi.nlm.nih.gov/pubmed/22233627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1625 |
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