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Structural rearrangements underlying ligand-gating in Kir channels

Inward rectifier potassium (Kir) channels are physiologically regulated by a wide range of ligands that all act on a common gate, although structural details of gating are unclear. Here we show, using small molecule fluorescent probes attached to introduced cysteines, the molecular motions associate...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Wang, Shizhen, Lee, Sun-Joo, Heyman, Sarah, Enkvetchakul, Decha, Nichols, Colin G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277880/
https://ncbi.nlm.nih.gov/pubmed/22233627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1625
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