Kinase activities of RIPK1 and RIPK3 can direct IFNβ synthesis induced by lipopolysaccharide

The innate immune response is a central element of the initial defense against bacterial and viral pathogens. Macrophages are key innate immune cells that upon encountering pathogen associated molecular patterns respond by producing cytokines, including Interferon-β (IFNβ). In this study, we identif...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Saleh, Danish, Najjar, Malek, Zelic, Matija, Shah, Saumil, Nogusa, Shoko, Polykratis, Apostolos, Paczosa, Michelle K., Gough, Peter J., Bertin, John, Whalen, Michael, Fitzgerald, Katherine, Slavov, Nikolai, Pasparakis, Manolis, Balachandran, Siddharth, Kelliher, Michelle, Mecsas, Joan, Degterev, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471631/
https://ncbi.nlm.nih.gov/pubmed/28461567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601717
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