Self-reactive T cells can escape clonal deletion in T-cell receptor V beta 8.1 transgenic mice.
To study the mechanisms of tolerance in detail, we have constructed transgenic mice expressing a V beta 8.1-D beta 2-J beta 2.3-C beta 2 T-cell receptor (TCR) gene. Since expression of V beta 8.1 is known to correlate with reactivity of CD4+CD8- T cells to minor lymphocyte-stimulating locus 1a (Mls-...
保存先:
| 出版年: | Proc Natl Acad Sci U S A |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1990
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54698/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2402496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.7135 |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|