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Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene.

To explore the role of bcl-2 in T-cell development, a bcl-2 transgene was introduced into mice expressing a T-cell receptor (TCR) transgene encoding reactivity for the mouse male antigen HY presented by the H-2Db class I antigen of the major histocompatibility complex (MHC). Normal thymic developmen...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Strasser, A, Harris, A W, von Boehmer, H, Cory, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43161/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8108419/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1376
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