Differential effects of Bcl-2 on T and B cells in transgenic mice.

We have produced bcl-2 transgenic mice by using a construct which mimics the t(14;18) translocation in human follicular lymphomas. Although lymphoid tissues from all transgenic mice contained high levels of human Bcl-2 protein, transgene expression was differentially regulated within the B- and T-ce...

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Bibliographic Details
Main Authors: Katsumata, M, Siegel, R M, Louie, D C, Miyashita, T, Tsujimoto, Y, Nowell, P C, Greene, M I, Reed, J C
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC50553/
https://ncbi.nlm.nih.gov/pubmed/1454823
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