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Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding.

A specific interaction between the class I major histocompatibility complex molecule Kb and thymocytes expressing the antigen receptor from the cytolytic T lymphocyte 2C enhances maturation of T cells of the CD8 lineage in transgenic mice. By analyzing transgenic mice backcrossed to Kbm mutant strai...

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Detalhes bibliográficos
Main Authors: Sha, W C, Nelson, C A, Newberry, R D, Pullen, J K, Pease, L R, Russell, J H, Loh, D Y
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54497/
https://ncbi.nlm.nih.gov/pubmed/2117275
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