Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice.

The bcl-2 gene, which is overexpressed in human follicular B-cell lymphomas, has been found to extend cellular lifespan through inhibition of apoptosis, or programmed cell death. However, the physiological role of the Bcl-2 protein in lymphocyte development is unclear. We have established a transgen...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Siegel, R M, Katsumata, M, Miyashita, T, Louie, D C, Greene, M I, Reed, J C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1495993/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.7003
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