Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.
In vitro, the overexpression of the bcl-2 protooncogene in cultured neurons has been shown to prevent apoptosis induced by neurotrophic factor deprivation. We have generated transgenic mice overexpressing the Bcl-2 protein in neurons, including motoneurons of the facial nucleus. We have tested wheth...
সংরক্ষণ করুন:
| প্রকাশিত: | Proc Natl Acad Sci U S A |
|---|---|
| প্রধান লেখক: | , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
National Academy of Sciences
1994
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43566/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8159744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.8.3309 |
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