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Interaction of PKR with single-stranded RNA
Although the antiviral kinase PKR was originally characterized as a double-stranded RNA activated enzyme it can be stimulated by RNAs containing limited secondary structure. Single-stranded regions in such RNAs contribute to binding and activation but the mechanism is not understood. Here, we demons...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469796/ https://ncbi.nlm.nih.gov/pubmed/28611419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03047-7 |
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