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JNK Activation Turns on LPS- and Gram-Negative Bacteria-Induced NADPH Oxidase-Dependent Suicidal NETosis

Neutrophils cast neutrophil extracellular traps (NETs) to ensnare microbial pathogens. Nevertheless, the molecular rheostats that regulate NETosis in response to bacteria are not clearly established. We hypothesized that stress-activated protein kinase or c-Jun N-terminal Kinase (SAPK/JNK) is a mole...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Khan, Meraj A., Farahvash, Armin, Douda, David N., Licht, Johann-Christoph, Grasemann, Hartmut, Sweezey, Neil, Palaniyar, Nades
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469795/
https://ncbi.nlm.nih.gov/pubmed/28611461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03257-z
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