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JNK Activation Turns on LPS- and Gram-Negative Bacteria-Induced NADPH Oxidase-Dependent Suicidal NETosis

Neutrophils cast neutrophil extracellular traps (NETs) to ensnare microbial pathogens. Nevertheless, the molecular rheostats that regulate NETosis in response to bacteria are not clearly established. We hypothesized that stress-activated protein kinase or c-Jun N-terminal Kinase (SAPK/JNK) is a mole...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Khan, Meraj A., Farahvash, Armin, Douda, David N., Licht, Johann-Christoph, Grasemann, Hartmut, Sweezey, Neil, Palaniyar, Nades
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469795/
https://ncbi.nlm.nih.gov/pubmed/28611461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03257-z
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