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SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx

Neutrophils cast neutrophil extracellular traps (NETs) to defend the host against invading pathogens. Although effective against microbial pathogens, a growing body of literature now suggests that NETs have negative impacts on many inflammatory and autoimmune diseases. Identifying mechanisms that re...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Douda, David Nobuhiro, Khan, Meraj A., Grasemann, Hartmut, Palaniyar, Nades
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352781/
https://ncbi.nlm.nih.gov/pubmed/25730848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414055112
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