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SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx
Neutrophils cast neutrophil extracellular traps (NETs) to defend the host against invading pathogens. Although effective against microbial pathogens, a growing body of literature now suggests that NETs have negative impacts on many inflammatory and autoimmune diseases. Identifying mechanisms that re...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352781/ https://ncbi.nlm.nih.gov/pubmed/25730848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414055112 |
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