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Transcriptional firing helps to drive NETosis

Neutrophils are short-lived innate immune cells. These cells respond quickly to stimuli, and die within minutes to hours; the relevance of DNA transcription in dying neutrophils remains an enigma for several decades. Here we show that the transcriptional activity reflects the degree of DNA decondens...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Khan, Meraj A., Palaniyar, Nades
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296899/
https://ncbi.nlm.nih.gov/pubmed/28176807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41749
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