Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage

Chromatin exhibits increased mobility on DNA damage, but the biophysical basis for this behavior remains unknown. To explore the mechanisms that drive DNA damage–induced chromosome mobility, we use single-particle tracking of tagged chromosomal loci during interphase in live yeast cells together wit...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Lawrimore, Josh, Barry, Timothy M., Barry, Raymond M., York, Alyssa C., Friedman, Brandon, Cook, Diana M., Akialis, Kristen, Tyler, Jolien, Vasquez, Paula, Yeh, Elaine, Bloom, Kerry
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469612/
https://ncbi.nlm.nih.gov/pubmed/28450453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0846
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