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Fork pausing allows centromere DNA loop formation and kinetochore assembly

De novo kinetochore assembly, but not template-directed assembly, is dependent on COMA, the kinetochore complex engaged in cohesin recruitment. The slowing of replication fork progression by treatment with phleomycin (PHL), hydroxyurea, or deletion of the replication fork protection protein Csm3 can...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cook, Diana M., Bennett, Maggie, Friedman, Brandon, Lawrimore, Josh, Yeh, Elaine, Bloom, Kerry
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243264/
https://ncbi.nlm.nih.gov/pubmed/30373818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806791115
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