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R-loops at centromeric chromatin contribute to defects in kinetochore integrity and chromosomal instability in budding yeast
R-loops, the byproduct of DNA–RNA hybridization and the displaced single-stranded DNA (ssDNA), have been identified in bacteria, yeasts, and other eukaryotic organisms. The persistent presence of R-loops contributes to defects in DNA replication and repair, gene expression, and genomic integrity. R-...
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| Publicado no: | Mol Biol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8098821/ https://ncbi.nlm.nih.gov/pubmed/33147102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-06-0379 |
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