Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage

Chromatin exhibits increased mobility on DNA damage, but the biophysical basis for this behavior remains unknown. To explore the mechanisms that drive DNA damage–induced chromosome mobility, we use single-particle tracking of tagged chromosomal loci during interphase in live yeast cells together wit...

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Publicado en:Mol Biol Cell
Main Authors: Lawrimore, Josh, Barry, Timothy M., Barry, Raymond M., York, Alyssa C., Friedman, Brandon, Cook, Diana M., Akialis, Kristen, Tyler, Jolien, Vasquez, Paula, Yeh, Elaine, Bloom, Kerry
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2017
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469612/
https://ncbi.nlm.nih.gov/pubmed/28450453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0846
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