Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage

Chromatin exhibits increased mobility on DNA damage, but the biophysical basis for this behavior remains unknown. To explore the mechanisms that drive DNA damage–induced chromosome mobility, we use single-particle tracking of tagged chromosomal loci during interphase in live yeast cells together wit...

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Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Lawrimore, Josh, Barry, Timothy M., Barry, Raymond M., York, Alyssa C., Friedman, Brandon, Cook, Diana M., Akialis, Kristen, Tyler, Jolien, Vasquez, Paula, Yeh, Elaine, Bloom, Kerry
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2017
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469612/
https://ncbi.nlm.nih.gov/pubmed/28450453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0846
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