Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression

There are marked differences in the spread and prevalence of HIV-1 subtypes worldwide, and differences in clinical progression have been reported. However, the biological reasons underlying these differences are unknown. Gag-protease is essential for HIV-1 replication, and Gag-protease-driven replic...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kiguoya, Marion W., Mann, Jaclyn K., Chopera, Denis, Gounder, Kamini, Lee, Guinevere Q., Hunt, Peter W., Martin, Jeffrey N., Ball, T. Blake, Kimani, Joshua, Brumme, Zabrina L., Brockman, Mark A., Ndung'u, Thumbi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469260/
https://ncbi.nlm.nih.gov/pubmed/28424286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00253-17
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