ロード中...

Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders

[Image: see text] Janus kinases (JAKs) regulate hematopoiesis via the cytokine-mediated JAK-STAT signaling pathway. JAKs contain tandem C-terminal pseudokinase (JH2) and tyrosine kinase (JH1) domains. The JAK2 pseudokinase domain adopts a protein kinase fold and, despite its pseudokinase designation...

詳細記述

保存先:
書誌詳細
出版年:ACS Med Chem Lett
主要な著者: Puleo, David E., Kucera, Kaury, Hammarén, Henrik M., Ungureanu, Daniela, Newton, Ana S., Silvennoinen, Olli, Jorgensen, William L., Schlessinger, Joseph
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2017
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467198/
https://ncbi.nlm.nih.gov/pubmed/28626521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00153
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!