Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53

Chronic inflammation (CI) is a risk factor for pancreatic cancer (PC) including the most common type, ductal adenocarcinoma (PDAC), but its role and the mechanisms involved are unclear. To investigate the role of CI in PC, we generated genetic mouse models with pancreatic specific CI in the presence...

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Publicat a:Oncogene
Autors principals: Swidnicka-Siergiejko, A K, Gomez-Chou, S B, Cruz-Monserrate, Z, Deng, D, Liu, Y, Huang, H, Ji, B, Azizian, N, Daniluk, J, Lu, W, Wang, H, Maitra, A, Logsdon, C D
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467016/
https://ncbi.nlm.nih.gov/pubmed/27991926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.461
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