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Mutational status of K- ras and TP53 genes in primary sarcomas of the heart

We investigated three patients with cardiac angiosarcomas and two with cardiac rhabdomyosarcomas, all for mutations at exons 5, 6, 7 and 8 of the p53 gene and at exon 1 of K- ras. No point mutations were observed in the p53 gene in any of the five cases; however, at exon 1 of K- ras, three patients...

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Detalhes bibliográficos
Main Authors: Garcia, J M, Gonzalez, R, Silva, J M, Dominguez, G, Vegazo, I S, Gamallo, C, Provencio, M, España, P, Bonilla, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363343/
https://ncbi.nlm.nih.gov/pubmed/10735503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1060
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