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Mutation Status of RAS, TP53, and SMAD4 is Superior to Mutation Status of RAS Alone for Predicting Prognosis after Resection of Colorectal Liver Metastases

PURPOSE: Somatic gene mutations have been increasingly recognized to impact prognosis following resection of colorectal liver metastases (CLM). We aimed to determine the impact of combinations of somatic mutations on survival in patients undergoing CLM resection. EXPERIMENTAL DESIGN: We identified p...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kawaguchi, Yoshikuni, Kopetz, Scott, Newhook, Timothy E., De Bellis, Mario, Chun, Yun Shin, Tzeng, Ching-Wei D., Aloia, Thomas A., Vauthey, Jean-Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774854/
https://ncbi.nlm.nih.gov/pubmed/31221662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0863
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