Deleterious Effect of RAS and Evolutionary High Risk TP53 Double Mutation in Colorectal Liver Metastases

OBJECTIVE: To assess the impact of somatic gene mutations on survival among patients undergoing resection of colorectal liver metastases (CLM). SUMMARY BACKGROUND DATA: Patients undergoing CLM resection have heterogeneous outcomes, and accurate risk stratification is necessary to optimize patient se...

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Detalhes bibliográficos
Publicado no:Ann Surg
Main Authors: Chun, Yun Shin, Passot, Guillaume, Yamashita, Suguru, Nusrat, Maliha, Katsonis, Panagiotis PhD, Loree, Jonathan M., Conrad, Claudius, Tzeng, Ching-Wei D., Xiao, Lianchun, Aloia, Thomas A., Eng, Cathy, Kopetz, Scott E., Lichtarge, Olivier, Vauthey, Jean-Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462436/
https://ncbi.nlm.nih.gov/pubmed/28767562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000002450
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