Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53

Chronic inflammation (CI) is a risk factor for pancreatic cancer (PC) including the most common type, ductal adenocarcinoma (PDAC), but its role and the mechanisms involved are unclear. To investigate the role of CI in PC, we generated genetic mouse models with pancreatic specific CI in the presence...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Swidnicka-Siergiejko, A K, Gomez-Chou, S B, Cruz-Monserrate, Z, Deng, D, Liu, Y, Huang, H, Ji, B, Azizian, N, Daniluk, J, Lu, W, Wang, H, Maitra, A, Logsdon, C D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467016/
https://ncbi.nlm.nih.gov/pubmed/27991926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.461
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