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Transcriptional regulation of mixed lineage kinase 3 by estrogen and its implication in ER-positive breast cancer pathogenesis

Mixed Lineage Kinase 3 (MLK3), also called as MAP3K11 is a tightly regulated MAP3K member but its cellular function is still not fully understood. Earlier we reported post-translational regulation of MLK3 by estrogen (E2) that inhibited the kinase activity and favored survival of ER(+) breast cancer...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Viswakarma, Navin, Nair, Rakesh Sathish, Sondarva, Gautam, Das, Subhasis, Ibrahimi, Lucas, Chen, Zhiyong, Sinha, Subhash, Rana, Basabi, Rana, Ajay
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464859/
https://ncbi.nlm.nih.gov/pubmed/28388540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16566
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