Augmentation of poly(ADP-ribose) polymerase-dependent neuronal cell death by acidosis

Tissue acidosis is a key component of cerebral ischemic injury, but its influence on cell death signaling pathways is not well defined. One such pathway is parthanatos, in which oxidative damage to DNA results in activation of poly(ADP-ribose) polymerase and generation of poly(ADP-ribose) polymers t...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Zhang, Jian, Li, Xiaoling, Kwansa, Herman, Kim, Yun Tai, Yi, Liye, Hong, Gina, Andrabi, Shaida A, Dawson, Valina L, Dawson, Ted M, Koehler, Raymond C, Yang, Zeng-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464694/
https://ncbi.nlm.nih.gov/pubmed/27381826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16658491
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