Augmentation of poly(ADP-ribose) polymerase-dependent neuronal cell death by acidosis

Tissue acidosis is a key component of cerebral ischemic injury, but its influence on cell death signaling pathways is not well defined. One such pathway is parthanatos, in which oxidative damage to DNA results in activation of poly(ADP-ribose) polymerase and generation of poly(ADP-ribose) polymers t...

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Bibliografiske detaljer
Udgivet i:J Cereb Blood Flow Metab
Main Authors: Zhang, Jian, Li, Xiaoling, Kwansa, Herman, Kim, Yun Tai, Yi, Liye, Hong, Gina, Andrabi, Shaida A, Dawson, Valina L, Dawson, Ted M, Koehler, Raymond C, Yang, Zeng-Jin
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464694/
https://ncbi.nlm.nih.gov/pubmed/27381826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16658491
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