Endonuclease G does not play an obligatory role in poly(ADP-ribose) polymerase-dependent cell death after transient focal cerebral ischemia

Activation of poly(ADP-ribose) polymerase (PARP) and subsequent translocation of apoptosis-inducing factor contribute to caspase-independent neuronal injury from N-methyl-d-aspartate, oxygen-glucose deprivation, and ischemic stroke. Some studies have implicated endonuclease G in the DNA fragmentatio...

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Autori principali: Xu, Zhenfeng, Zhang, Jian, David, Karen K., Yang, Zeng-Jin, Li, Xiaoling, Dawson, Ted M., Dawson, Valina L., Koehler, Raymond C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904146/
https://ncbi.nlm.nih.gov/pubmed/20427721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00747.2009
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