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Poly(ADP-ribose) Signals to Mitochondrial AIF: A Key Event in Parthanatos
Poly(ADP-ribose) polymerase-1 (PARP-1) plays a pivotal role in multiple neurologic diseases by mediating caspase-independent cell death, which has recently been designated parthanatos to distinguish it from other forms of cell death such as apoptosis, necrosis and autophagy. Mitochondrial apoptosis-...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752872/ https://ncbi.nlm.nih.gov/pubmed/19332058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.03.020 |
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