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Poly(ADP-ribose) Signals to Mitochondrial AIF: A Key Event in Parthanatos

Poly(ADP-ribose) polymerase-1 (PARP-1) plays a pivotal role in multiple neurologic diseases by mediating caspase-independent cell death, which has recently been designated parthanatos to distinguish it from other forms of cell death such as apoptosis, necrosis and autophagy. Mitochondrial apoptosis-...

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Detalhes bibliográficos
Main Authors: Wang, Yingfei, Dawson, Valina L., Dawson, Ted M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752872/
https://ncbi.nlm.nih.gov/pubmed/19332058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.03.020
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