P08.12 Tolerability and initial efficacy of convection-enhanced delivery of combinatorial IL-13RA2 and EphA2 targeted cytotoxins to dogs with spontaneous intracranial malignant gliomas

Introduction: The interleukin 13 receptor alpha 2 (IL-13RA2) and EphA2 receptor are attractive molecular targets for malignant gliomas, being expressed in ~90% of canine and human malignant gliomas, and virtually absent in normal brain. We have generated potent IL-13 and ephrin-A1 (eA1)-based cytoto...

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發表在:Neuro Oncol
Main Authors: Rossmeisl, J. H., Herpai, D., Robertson, J. L., Dickinson, P. J., Tatter, S. B., Debinski, W.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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POSTER PRESENTATIONS
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464154/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.202
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