Phase I trial of convection-enhanced delivery of IL13RA2 and EPHA2 receptor targeted cytotoxins in dogs with spontaneous intracranial gliomas

BACKGROUND: The interleukin-13 receptor alpha 2 (IL13RA2) and ephrin type A receptor 2 (EPHA2) are attractive therapeutic targets, being expressed in ~90% of canine and human gliomas, and absent in normal brain. Clinical trials using an earlier generation IL-13 based cytotoxin showed encouraging cli...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Rossmeisl, John H, Herpai, Denise, Quigley, Mindy, Cecere, Thomas E, Robertson, John L, D’Agostino, Ralph B, Hinckley, Jonathan, Tatter, Stephen B, Dickinson, Peter J, Debinski, Waldemar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Basic and Translational Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992889/
https://ncbi.nlm.nih.gov/pubmed/32812637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa196
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller