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P08.12 Tolerability and initial efficacy of convection-enhanced delivery of combinatorial IL-13RA2 and EphA2 targeted cytotoxins to dogs with spontaneous intracranial malignant gliomas
Introduction: The interleukin 13 receptor alpha 2 (IL-13RA2) and EphA2 receptor are attractive molecular targets for malignant gliomas, being expressed in ~90% of canine and human malignant gliomas, and virtually absent in normal brain. We have generated potent IL-13 and ephrin-A1 (eA1)-based cytoto...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5464154/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.202 |
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