Vaccination with EphA2-derived T cell-epitopes promotes immunity against both EphA2-expressing and EphA2-negative tumors

BACKGROUND: A novel tyrosine kinase receptor EphA2 is expressed at high levels in advanced and metastatic cancers. We examined whether vaccinations with synthetic mouse EphA2 (mEphA2)-derived peptides that serve as T cell epitopes could induce protective and therapeutic anti-tumor immunity. METHODS:...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Transl Med
Päätekijät: Hatano, Manabu, Kuwashima, Naruo, Tatsumi, Tomohide, Dusak, Jill E, Nishimura, Fumihiko, Reilly, Karlyne M, Storkus, Walter J, Okada, Hideho
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2004
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535538/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15563374/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1479-5876-2-40
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia