Vaccination with EphA2-derived T cell-epitopes promotes immunity against both EphA2-expressing and EphA2-negative tumors

BACKGROUND: A novel tyrosine kinase receptor EphA2 is expressed at high levels in advanced and metastatic cancers. We examined whether vaccinations with synthetic mouse EphA2 (mEphA2)-derived peptides that serve as T cell epitopes could induce protective and therapeutic anti-tumor immunity. METHODS:...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hatano, Manabu, Kuwashima, Naruo, Tatsumi, Tomohide, Dusak, Jill E, Nishimura, Fumihiko, Reilly, Karlyne M, Storkus, Walter J, Okada, Hideho
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535538/
https://ncbi.nlm.nih.gov/pubmed/15563374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-2-40
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados