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CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome
Large genome-mapping consortia and thousands of genome-wide association studies have identified non-protein coding elements in the genome as a having a central role in various biological processes. However, decoding the function of the millions of putative regulatory elements discovered in these stu...
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| Publicado no: | Nat Biotechnol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5462860/ https://ncbi.nlm.nih.gov/pubmed/28369033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3853 |
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